[Central serous chorioretinopathy: etiology and pathogenesis]
Vestnik Oftalmologii
|July 9, 2010
Summary
Stress significantly impacts central serous chorioretinopathy (CSC) development and recurrence. Understanding the stress response
Area of Science:
- Ophthalmology
- Retinology
- Endocrinology
Context:
- Central serous chorioretinopathy (CSC) is a significant retinal disease.
- The etiology and pathogenesis of CSC remain areas of active research.
Purpose:
- To review the literature on the etiology and pathogenesis of central serous chorioretinopathy (CSC).
- To explore the impact of stress on the development and recurrence of CSC.
Summary:
- The review covers historical facts, basic theories, and classification of CSC.
- It highlights the role of stress-induced physiological changes, including hypertensive reactions and hormonal imbalances (cortisol, pituitary-thyroid), in CSC pathogenesis.
- These stress-related factors are increasingly implicated in CSC recurrence and complications.
Impact:
- Provides a comprehensive overview of current knowledge on CSC etiology and pathogenesis.
- Emphasizes the critical role of the stress response in CSC development and management.
- Informs future research directions for understanding and treating CSC.
Related Concept Videos
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:22Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
01:26Encephalitis ll: Pathophysiology
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
01:29Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...