Related Experiment Video
Updated: Jun 11, 2026
Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
Published on: November 22, 2024
[Improved experimental varicocele increases follicle-stimulating hormone and reduces inhibin B in rats]
Ying-Chuan Jiang1, Jian-Jun Yu, Tao Yan
1Department of Urology, The 6th PeopleS Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China. jyc_jiang@163.com
Objective:
To evaluate the effects of improved experimental left varicocele (ELV) on follicle-stimulating hormone (FSH) and inhibin B (InhB).
Methods:
ELV models were established by the improved method in 30 SD rats, and another 30 were included in a sham operation group as controls. Three months after the operation, the concentrations of the FSH and InhB were assayed by ELISA.
Results:
The concentration of FSH in the serum was significantly higher in the experimental group ([37.56 +/- 9.72] ng/ml) than in the control ([26.69 +/- 5.33] ng/ml) (P < 0.05), while that of InhB significantly lower in the former ([349.93 +/- 99.48] pg/ml) than in the latter ([768. 83 +/- 146.96] pg/ml) (P < 0.05).
Conclusion:
Improved ELV can increase FSH and reduce InhB in rats, which may be associated with subfertility.
