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Related Concept Videos

Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

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Mass Spectrometry: Branched Alkane Fragmentation01:29

Mass Spectrometry: Branched Alkane Fragmentation

This lesson delves into the mass spectrometry of branched alkane fragmentation. Branched alkanes possess secondary or tertiary carbon atoms, which generate relatively stable carbocations if the cleavage occurs at the branching point. The high stability of carbocations drives the instant fragmentation of branched alkanes. Accordingly, the branched alkane's molecular ion peak is very weak or invisible in the mass spectra, especially in comparison to a linear alkane.
2° Amines to N-Nitrosamines: Reaction with NaNO201:20

2° Amines to N-Nitrosamines: Reaction with NaNO2

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Free Energy Changes for Nonstandard States03:25

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¹H NMR of Conformationally Flexible Molecules: Temporal Resolution00:52

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At room temperature, the chair conformer of cyclohexane undergoes rapid ring flipping between two equivalent chair conformers at a rate of approximately 105 times per second. These two chair conformers are in equilibrium. The rapid ring flipping results in the interconversion of the axial proton to an equatorial proton and an equatorial to the axial proton. Such interconversions are too rapid and cannot be detected on the NMR timescale. Hence, the NMR spectrometer cannot distinguish between the...

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Updated: Jun 11, 2026

Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials
09:05

Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials

Published on: May 15, 2015

Nitromethane decomposition under high static pressure.

Margherita Citroni1, Roberto Bini, Marco Pagliai

  • 1European Laboratory for Nonlinear Spectroscopy (LENS), via Nello Carrara 1, 50019 Sesto Fiorentino, Italia. margherita@lens.unifi.it

The Journal of Physical Chemistry. B
|July 9, 2010
PubMed
Summary
This summary is machine-generated.

High pressure transforms nitromethane into a disordered polymer. Upon release, this polymer decomposes into N-methylformamide, a molecule with a peptide bond, offering new insights into high-pressure chemistry.

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Last Updated: Jun 11, 2026

Supercritical Nitrogen Processing for the Purification of Reactive Porous Materials
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Published on: May 15, 2015

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07:49

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes

Published on: August 5, 2016

Area of Science:

  • Chemistry
  • Materials Science
  • Physical Chemistry

Background:

  • Nitromethane is a simple organic molecule with complex high-pressure behavior.
  • Understanding pressure-induced reactions is crucial for materials science and chemical synthesis.

Purpose of the Study:

  • To investigate the room-temperature pressure-induced reaction of nitromethane.
  • To elucidate the reaction mechanism, products, and structural evolution under high pressure.
  • To explore the effect of electronic excitation on the high-pressure reaction.

Main Methods:

  • Infrared spectroscopy in a diamond anvil cell.
  • Ab initio molecular dynamics simulations.
  • High-pressure experiments with 458 nm laser irradiation.

Main Results:

  • Nitromethane forms a 3D disordered polymer at 32.2-35.5 GPa.
  • The reaction mechanism involves bimolecular character and aci-ion formation.
  • Decompression yields N-methylformamide; laser irradiation lowers reaction threshold and forms methanol.

Conclusions:

  • Pressure induces a novel polymerization of nitromethane with unique decompression behavior.
  • The formation of N-methylformamide highlights new pathways in high-pressure chemistry.
  • Electronic excitation offers a route to control high-pressure reactions and product formation.