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Updated: Jun 11, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Synchronous oral paracoccidioidomycosis and oral squamous cell carcinomas with submandibular enlargement
Rebeca Souza Azevedo1, Adriele Ferreira Gouvêa, Márcio Ajudarte Lopes
1Oral Pathology, School of Dentistry, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil. rebecadesa@gmail.com
Abstract:
Oral paracoccidioidomycosis and oral squamous cell carcinoma may occur in the same patient. As both lesions may present similar clinical and histopathological features, the diagnosis is sometimes challenging. This paper describes the case of a 54-year-old male who was a farm worker and heavy alcohol and tobacco user. He developed paracoccidioidomycosis and two lesions of squamous cell carcinoma in the oral cavity. During the follow-up, the patient presented enlargement of the submandibular lymph nodes, which was thought to be regional metastasis but was diagnosed as paracoccidioidomycosis. Therefore, the significance of this association is emphasized and discussed.
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