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Updated: Jun 11, 2026

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
Published on: March 24, 2018
Ionic cyclodextrins in ionic liquid matrices as chiral stationary phases for gas chromatography
Ke Huang1, Xiaotong Zhang, Daniel W Armstrong
1University of Texas at Arlington, Department of Chemistry and Biochemistry, Arlington, TX 76019, USA.
Abstract:
Ionic liquids (ILs) are used to dissolve ionic cyclodextrin (CD) derivatives to produce a new type of gas chromatographic chiral stationary phase. Compared to a previous study with neutral cyclodextrin chiral selectors, the new ionic liquid-based stationary phase exhibits broader enantioselectivities, up to seven times higher efficiencies, and greater thermal stabilities. When compared to the analogous commercial column with polysiloxane matrix, it exhibits different enantioselectivities, more symmetric peak shapes and some complementary enantioseparations. The most profound separation enhancements are usually found for more polar analytes.
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