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Updated: Jun 11, 2026

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
Published on: June 8, 2016
Early experience with combined use of two plant-based hemostatic agents
Tsutomu Matsushita1, Shinsuke Masuda, Tomoya Inoue
1Department of Cardiovascular Surgery, Maizuru Mutual Hospital, Maizuru, Kyoto, Japan. atmatsu@tokyonet.com.au
Abstract:
Bleeding from anastomoses, which is more effectively controlled with topical hemostatic agents than with sutures, has been one of the major problems in cardiovascular surgery. We describe a novel hemostatic technique using microporous polysaccharide hemosphere (Arista; Medafor Inc, Minneapolis, MN) in conjunction with a patch of oxidized regenerated cellulose (Nu-Knit; Ethicon, Johnson & Johnson, Somerville, NJ). Both of them are plant-based products and eliminate the risk of animal-borne or human-borne contaminants and have bactericidal advantages.
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