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Updated: Jun 11, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Epidemiology of hypertension in the elderly with chronic kidney disease
Michael J Fischer1, Ann M O'Hare
1Jesse Brown VA Medical Center, Chicago, IL 60141, USA. fischerm@uic.edu <fischerm@uic.edu>
Insights
Hypertension is common and poorly controlled in older adults with chronic kidney disease (CKD). More research is needed to understand optimal blood pressure management strategies for this growing population.
Area of Science:
- Gerontology
- Nephrology
- Cardiology
Background:
- Aging populations are experiencing increased rates of chronic conditions like hypertension and chronic kidney disease (CKD).
- Hypertension is highly prevalent in elderly individuals with CKD, frequently remaining uncontrolled despite medication.
- Current guidelines for blood pressure control are met by fewer than one-third of elderly CKD patients.
Purpose of the Study:
- To review the current evidence on hypertension management in older adults with CKD.
- To highlight the complexities and distinctiveness of hypertension treatment outcomes in this demographic.
- To identify the need for further research in this area.
Main Methods:
- Review of available observational studies and clinical trials.
- Analysis of data from nationally representative samples and outpatient populations.
- Synthesis of existing literature on hypertension and CKD in the elderly.
Main Results:
- Hypertension is a significant comorbidity in elderly patients with CKD.
- Blood pressure control is often inadequate in this population.
- The relationship between hypertension treatment and clinical outcomes in older adults with CKD differs from younger individuals.
Conclusions:
- Evidence for guiding hypertension management in elderly CKD patients is limited.
- The association between hypertension, its treatment, and clinical events in this group requires further investigation.
- Larger, robust analyses are necessary to inform clinical practice and improve patient outcomes.
Abstract:
As the population of the United States ages, the prevalence of age-related chronic conditions such as hypertension and chronic kidney disease (CKD) will also increase. Available studies in nationally representative samples and select outpatient populations indicate that hypertension is very common in older adults with CKD, and despite the use of medication it is often poorly controlled. Generally, less than one-third of the elderly patients with CKD achieve a level of blood pressure control consistent with that of the current guideline recommendations. However, limited evidence is available from observational studies and clinical trials to inform management of hypertension in the elderly population with CKD. The available published data suggest that the relationship between clinical outcomes and the treatment of hypertension among older adults with CKD is complex and distinct from that of their younger counterparts. Larger and more robust analyses are needed for a better understanding of the association between hypertension, its treatment, and clinical events in elderly patients with CKD.
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