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Updated: Jun 11, 2026

A Protocol for Housing Mice in an Enriched Environment
09:30

A Protocol for Housing Mice in an Enriched Environment

Published on: June 8, 2015

Mice prefer draught-free housing.

T C Krohn1, A K Hansen

  • 1Centre for Applied Laboratory Animal Research, Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, 1870 Frederiksberg C, Denmark. tkr@life.ku.dk

Laboratory Animals
|July 9, 2010
PubMed
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Mice housed in individually ventilated cage (IVC) systems react to air draughts. However, they are unaffected by increased air changes if the airflow is draught-free, highlighting the need for comfortable IVC systems.

Area of Science:

  • Laboratory animal science
  • Animal welfare science
  • Rodent housing systems

Background:

  • Individually ventilated cage (IVC) systems are increasingly used for housing rodents.
  • IVC systems offer protection against infections for animals and allergens for staff.
  • High ventilation rates in IVC systems can create uncomfortable air draughts at the animal level.

Purpose of the Study:

  • To evaluate mouse preferences for different levels of air speed and air change rates within cages.
  • To determine the impact of draughts versus high air change rates on mouse behavior and welfare.

Main Methods:

  • Experimental setup to control and vary air speed and air change rates inside rodent cages.
  • Observational studies on mouse behavior and preference in response to different airflow conditions.

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Last Updated: Jun 11, 2026

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Main Results:

  • Mice demonstrated clear reactions to air draughts within the cage environment.
  • Mice did not exhibit negative responses to high air change rates when the airflow was draught-free.

Conclusions:

  • Air draughts are a significant welfare concern for mice in IVC systems.
  • Draught-free IVC systems are crucial for maintaining mouse comfort and well-being.
  • Ventilation strategies should prioritize eliminating draughts over simply increasing air exchange rates.