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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
Should South Africa be performing nucleic acid testing on HIV enzyme-linked immunosorbent assay-negative samples?
Natasha Gous1, Lesley Scott, Olga Perovic
1Department of Molecular Medicine and Haematology, School of Pathology, University of Witwatersrand, Parktown, Johannesburg 2193, South Africa.
Journal of Clinical Microbiology
|July 9, 2010
Abstract:
The frequency of acute HIV infection (AHI) among HIV-1 enzyme-linked immunosorbent assay (ELISA)-negative samples received from general hospital patient admissions was assessed. Of 3,005 samples pooled for nucleic acid testing, a prevalence of 0.13% was found. Pooled nucleic acid testing may be feasible for low-cost identification of AHI in high-prevalence settings.
