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Related Experiment Video

Updated: Jun 11, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

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Published on: September 20, 2024

Peripheral ocular aberrations in mild and moderate keratoconus.

David A Atchison1, Ankit Mathur, Scott A Read

  • 1School of Optometry and Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia. d.atchison@qut.edu.au

Investigative Ophthalmology & Visual Science
|July 9, 2010
PubMed
Summary

Keratoconus significantly alters peripheral ocular aberrations, with moderate cases showing more pronounced changes. Vertical coma is the primary higher-order aberration observed in keratoconus patients across their visual field.

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Last Updated: Jun 11, 2026

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05:46

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Published on: September 20, 2024

Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Keratoconus is a progressive corneal ectasia affecting visual quality.
  • Understanding ocular aberrations is crucial for diagnosing and managing visual impairments.

Purpose of the Study:

  • To investigate how keratoconus influences peripheral ocular aberrations.
  • To compare aberration patterns between mild and moderate keratoconus and emmetropic individuals.

Main Methods:

  • Ocular aberrations were measured in mild (n=7) and moderate (n=5) keratoconus patients and emmetropic controls.
  • Measurements covered a 42° horizontal × 32° vertical visual field using a modified aberrometer.

Main Results:

  • Keratoconus induced field-dependent aberrations, particularly in the vertical meridian.
  • Higher magnitudes of aberrations, including spherical equivalent and astigmatism, were found in the inferior visual field.
  • Moderate keratoconus exhibited greater aberration changes and magnitudes compared to mild keratoconus.

Conclusions:

  • Keratoconus significantly increases the rate of change and magnitude of peripheral ocular aberrations compared to emmetropia.
  • Vertical coma was identified as the dominant higher-order aberration in keratoconus patients across the visual field.
  • Visual field aberration patterns differ between mild and moderate keratoconus severity.