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Real-Time Quantification of Reactive Oxygen Species in Neutrophils Infected with Meningitic Escherichia Coli
Published on: April 20, 2021
[Rhodotorula glutinis sepsis. A case report]
Fabrizio Pulvirenti1, Paolo Pasqua, Elio Falzone
1U.O. di Malattie Infettive, Azienda Ospedaliera Umberto I, Enna, Italy.
Le Infezioni in Medicina
|July 9, 2010
Summary
Fungal sepsis, often overlooked, causes antibiotic-resistant fever in immunocompromised patients. Early blood cultures are crucial for diagnosing fungal infections like Rhodotorula glutinis, especially with central venous catheters (CVCs).
Area of Science:
- Mycology
- Infectious Diseases
- Clinical Microbiology
Background:
- Fungal sepsis is a significant cause of persistent fever unresponsive to antibiotics.
- It is frequently underdiagnosed, particularly in immunocompromised individuals with conditions like diabetes.
Observation:
- The abstract highlights the importance of considering fungal infections in patients with prolonged immune depression.
- Blood cultures, ideally during antibiotic withdrawal, are vital for identifying fungal pathogens.
- A specific case of systemic Rhodotorula glutinis infection associated with central venous catheter (CVC) use is presented.
Findings:
- Rhodotorula glutinis can cause systemic fungal infections.
- The presence of a CVC can be a risk factor for fungal sepsis.
- Timely diagnosis through blood cultures is critical for effective treatment.
Implications:
- Increased clinical suspicion for fungal sepsis in at-risk populations is warranted.
- Diagnostic protocols should include fungal blood cultures, especially in febrile patients with CVCs.
- This case underscores the need to recognize and manage opportunistic fungal infections effectively.
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