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Cardiorenal risk factors

Barry M Wall1

  • 1Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, Tennessee 38104, USA. Barry.Wall@va.gov

The American Journal of the Medical Sciences
|July 9, 2010
PubMed

Insights

Chronic kidney disease (CKD) significantly increases cardiovascular risk. Early assessment of glomerular filtration rate and albuminuria aids in stratifying patient risk for better cardiovascular outcomes.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Chronic kidney disease (CKD) is increasingly prevalent, affecting approximately 11% of the U.S. population.
  • CKD is linked to impaired cardiac function and structure, known as chronic renocardiac syndrome.
  • This syndrome elevates the risk of adverse cardiovascular events.

Purpose of the Study:

  • To highlight the association between CKD and adverse cardiovascular outcomes.
  • To emphasize the importance of CKD markers in risk stratification.
  • To advocate for the inclusion of CKD assessment in routine patient evaluation.

Main Methods:

  • Review of numerous studies demonstrating the link between CKD and adverse outcomes.
  • Analysis of CKD definition based on glomerular filtration rate and albuminuria.
  • Consideration of cost-effectiveness for diagnostic markers.

Main Results:

  • CKD, defined by reduced glomerular filtration rate and/or albuminuria, is consistently associated with adverse cardiovascular and renal outcomes.
  • These markers are readily available with minimal cost.

Conclusions:

  • Albuminuria and glomerular filtration rate are crucial indicators for cardiovascular risk stratification.
  • Integrating CKD assessment with traditional cardiovascular risk factors can improve patient management.
  • Early identification and management of CKD are vital for preventing cardiovascular complications.

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