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T Cells Capture Bacteria by Transinfection from Dendritic Cells
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Human mucosal associated invariant T cells detect bacterially infected cells

Marielle C Gold1, Stefania Cerri, Susan Smyk-Pearson

  • 1Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America. goldm@ohsu.edu

Plos Biology
|July 9, 2010
PubMed
Summary

Mucosal associated invariant T (MAIT) cells, a type of CD8+ T cell, are crucial for controlling Mycobacterium tuberculosis (Mtb) infection. These cells are decreased in active tuberculosis patients but enriched in the lungs, suggesting a key role in bacterial infection detection.

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