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Related Experiment Videos

Chemotherapy-induced acral erythema.

B R Baack1, W H Burgdorf

  • 1Department of Dermatology, University of New Mexico, Albuquerque 87131.

Journal of the American Academy of Dermatology
|March 1, 1991
PubMed
Summary

Chemotherapy can cause acral erythema, a skin reaction affecting hands and feet. Different chemotherapy drugs may trigger this side effect through various underlying mechanisms.

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Area of Science:

  • Oncology
  • Dermatology

Background:

  • Acral erythema is a known side effect of various chemotherapy treatments.
  • The clinical presentation of chemotherapy-induced acral erythema can be diverse.

Purpose of the Study:

  • To review the existing literature on chemotherapy-induced acral erythema.
  • To explore potential differing mechanisms responsible for the observed acral changes.

Main Methods:

  • Literature review of studies reporting chemotherapy-induced acral erythema.
  • Analysis of clinical presentations and associated chemotherapy regimens.

Main Results:

  • Chemotherapy-induced acral erythema is associated with multiple chemotherapy regimens.
  • Clinical manifestations of acral erythema vary significantly.

Conclusions:

  • Diverse mechanisms likely contribute to the heterogeneous presentation of chemotherapy-induced acral erythema.
  • Further research is needed to elucidate specific pathways for different chemotherapy agents.

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