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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Updated: Jun 11, 2026

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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Published on: January 22, 2011

NIHN Direct. ONC keeps it simple in effort to jumpstart data exchange.

Chris Dimick1

  • 1chris.dimick@ahima.org

Journal of AHIMA
|July 10, 2010
PubMed
Summary

The federal government is simplifying the nationwide health information network to support the meaningful use program. This change will impact how Health Information Exchanges (HIEs) operate and integrate with national standards.

Area of Science:

  • Health Informatics
  • Public Health Policy
  • Information Systems

Background:

  • The nationwide health information network (HIN) is undergoing a simplification initiative by the federal government.
  • This strategic change aims to better support the meaningful use program, a key driver for electronic health record adoption and interoperability.
  • Understanding the implications for Health Information Exchanges (HIEs) is crucial for stakeholders in health data management.

Purpose of the Study:

  • To analyze the impact of the federal government's simplified nationwide health information network on Health Information Exchanges (HIEs).
  • To clarify the operational and strategic consequences for HIEs in the context of the meaningful use program.
  • To provide insights into how HIEs can adapt to the evolving federal health IT landscape.

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Main Methods:

  • Review of federal government publications and policy documents regarding the HIN and meaningful use program.
  • Analysis of existing literature on Health Information Exchange functionalities and challenges.
  • Comparative assessment of current HIE capabilities versus the proposed simplified HIN model.

Main Results:

  • The simplified HIN may reduce the complexity of data exchange for HIEs.
  • HIEs might need to adjust their technical infrastructure and data governance policies.
  • Potential for increased focus on core interoperability functions, streamlining meaningful use attestation.

Conclusions:

  • The federal government's initiative presents both challenges and opportunities for HIEs.
  • Adaptation will be key for HIEs to maintain relevance and effectiveness in supporting meaningful use.
  • Further research is needed to quantify the specific impacts on HIE performance and patient data accessibility.