Related Experiment Video
Updated: Jun 11, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Cervical ectopic thymus masquerading as metastatic thyroid papillary carcinoma
Amit K Chowhan1, Vijay S B Kinnera, Mutheeswaraiah Yootla
1Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India. chowhanpath@gmail.com
Abstract:
Cervical ectopic thymus (CET), a common embryological anomaly detected incidentally at autopsy, is rarely described in clinical patients. Furthermore, aberrant cervical thymic tissue is an infrequently reported cause of paediatric neck masses. We report a 12-year-old female presenting with multinodular thyroid swelling since seven years of age. FNAC revealed adenomatous goitre with suspicious cystic papillary neoplastic foci, for which she underwent total thyroidectomy along with excision of a nodular swelling near the lower pole of the right thyroid lobe which was per-operatively suspected to be a lymph node. Histopathological examination revealed a follicular variant papillary carcinoma of the thyroid with background thyroiditis, and a nodule of ectopic thymic tissue. Though the presence of CET is rare, one should be aware of this entity, especially in children because it may be confused with lymph node metastasis which may lead to morbid radical neck dissection.
Related Concept Videos
Hyperthyroidism II: Pathophysiology
Hyperthyroidism I: Introduction
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Graves Disease II: Pathophysiology
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Goiter

