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3D PET using a conventional multislice tomograph without septa.

S R Cherry1, M Dahlbom, E J Hoffman

  • 1Division of Nuclear Medicine and Biophysics, University of California, Los Angeles School of Medicine 90024-1721.

Journal of Computer Assisted Tomography
|July 1, 1991
PubMed
Summary
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Removing septa from positron emission tomography (PET) scanners significantly boosts sensitivity and count rates for 3D imaging. This modification enhances data collection for improved 3D PET scans.

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Physics

Background:

  • Conventional multislice positron emission tomography (PET) scanners utilize interplane septa to reduce scatter and improve image resolution.
  • However, septa limit the collection of coincidence events, thereby reducing overall system sensitivity.

Purpose of the Study:

  • To evaluate the performance of a modified multislice PET scanner operating without interplane septa for three-dimensional (3D) data acquisition and reconstruction.
  • To assess the impact of septa removal on system sensitivity, image quality, and count rate performance.

Main Methods:

  • A conventional multislice PET scanner was modified by removing interplane septa.
  • A 3D filtered backprojection algorithm was implemented for image reconstruction.

Related Experiment Videos

  • Performance was evaluated using computer simulations, phantom measurements, and human brain studies with various radiotracers (18F-FDG, 18F-FDOPA, H2 15O).

    • Main Results:

    • System sensitivity increased by a factor of 7 after septa removal.
    • Scatter fraction increased from 16% to 41%.
    • Transaxial resolution degraded by 11% in outer planes, and axial resolution degraded slightly (6.9 to 7.7 mm FWHM).
    • Maximum count rate performance improved, with higher achievable count rates at lower radiotracer concentrations.

    Conclusions:

    • Septa removal in PET scanners significantly enhances system sensitivity and maximum count rates, enabling more efficient data acquisition for 3D imaging.
    • While there is a trade-off with increased scatter and slight resolution degradation, the benefits for 3D PET imaging are substantial.
    • The modified scanner demonstrates improved performance for brain imaging studies under various conditions.