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Published on: July 22, 2021
Burden of childhood-onset arthritis
Lakshmi N Moorthy1, Margaret Ge Peterson, Afton L Hassett
1Robert Wood Johnson Medical School-UMDNJ, Dept, of Pediatrics Room 1361, 89 French Street, New Brunswick, NJ, USA. moorthln@umdnj.edu.
Insights
Juvenile arthritis (JA) causes chronic inflammation and disability in children, impacting their quality of life and leading to long-term health issues. Addressing JA requires tailored interventions for better patient outcomes and reduced societal costs.
Area of Science:
- Pediatric Rheumatology
- Public Health
- Disability Studies
Background:
- Juvenile arthritis (JA) encompasses chronic inflammatory conditions leading to childhood erosive arthritis and potential disability.
- JA significantly impairs children's physical function through pain, stiffness, and swelling, with potential complications like blindness from uveitis.
Purpose of the Study:
- To review the multifaceted burden of juvenile arthritis on patients, families, and society.
- To highlight key areas of impact including disability, visual outcomes, medical complications, and quality of life.
Main Methods:
- Literature review of existing studies on juvenile arthritis.
- Analysis of patient disability, visual outcomes, medical complications, physical activity, HRQOL, emotional impact, pain, healthcare utilization, economic impact, caregiver burden, transition, education, and sexuality.
Main Results:
- JA imposes a substantial burden on patients' and families' lives, affecting health-related quality of life, physical function, and visual outcomes.
- The condition impacts school and home functioning, necessitating interventions for improved transition to adult care, vocational outcomes, and cost reduction.
Conclusions:
- Effective, tailored interventions are crucial to mitigate the impact of juvenile arthritis.
- Addressing JA requires a comprehensive approach to improve patient functioning, support caregivers, and reduce societal healthcare costs.
Abstract:
Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and back pain, heel pain, swelling of joints and morning stiffness, contractures, pain, and anterior uveitis leading to blindness. As children who have juvenile arthritis reach adulthood, they face possible continuing disease activity, medication-associated morbidity, and life-long disability and risk for emotional and social dysfunction. In this article we will review the burden of juvenile arthritis for the patient and society and focus on the following areas: patient disability; visual outcome; other medical complications; physical activity; impact on HRQOL; emotional impact; pain and coping; ambulatory visits, hospitalizations and mortality; economic impact; burden on caregivers; transition issues; educational occupational outcomes, and sexuality.The extent of impact on the various aspects of the patients', families' and society's functioning is clear from the existing literature. Juvenile arthritis imposes a significant burden on different spheres of the patients', caregivers' and family's life. In addition, it imposes a societal burden of significant health care costs and utilization. Juvenile arthritis affects health-related quality of life, physical function and visual outcome of children and impacts functioning in school and home. Effective, well-designed and appropriately tailored interventions are required to improve transitioning to adult care, encourage future vocation/occupation, enhance school function and minimize burden on costs.
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