Related Experiment Videos
Screening of clones containing altered DNA conformations by plasmid topoprofile shift
1Molecular Biophysics Unit, Indian Institute of Science, Bangalore.
Journal of Biochemical and Biophysical Methods
|February 1, 1991
Abstract:
DNA topoprofile of supercoiled plasmid is influenced by the presence of altered structures in some stretches. We describe a non-radioactive method for screening the clones containing such altered structures.