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Updated: Jun 11, 2026

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Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
[Submucosal endoscopic dissection]
1Departamento de Gastroenterología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico. matanimoto@prodigy.net.mx
Revista De Gastroenterologia De Mexico
|July 10, 2010
Summary
Endoscopic submucosal dissection (ESD) is a safe endoscopic procedure for early gastrointestinal cancers. Proper training and established indications are crucial for its successful application, potentially replacing surgery.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Oncology
Context:
- Endoscopic submucosal dissection (ESD) is an advanced endoscopic technique.
- It expands therapeutic options for early-stage gastrointestinal cancers (T1mN0).
Purpose:
- To review current training requirements for ESD.
- To outline established indications for ESD.
- To discuss available devices for ESD procedures.
Summary:
- Indications for ESD in early GI cancer include differentiated mucosal lesions (non-ulcerated or <3cm ulcerated), poorly-differentiated mucosal lesions (<2cm non-ulcerated), and submucosal invasive lesions (<3cm, <500µm depth).
- Submucosal elevation commonly uses saline with epinephrine and indigo. Technological advancements enhance safety.
- Training necessitates at least 30 animal model procedures before patient intervention.
Impact:
- ESD is a safe endoscopic alternative to surgery for selected early gastrointestinal malignancies.
- It requires specialized training and adherence to specific indications for optimal outcomes.
- The technique offers a less invasive therapeutic option compared to traditional surgical resections.
