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Updated: Jun 11, 2026
10:02
State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Newborn frontal horn cysts: cause for concern?
1Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Summary
Frontal horn cysts (FHC) are common in newborns and appear benign. These cysts do not impact neurodevelopmental outcomes in infants, offering reassurance to parents.
Area of Science:
- Neonatal neurology
- Pediatric neuroimaging
- Developmental pediatrics
Background:
- Frontal horn cysts (FHC) are a finding on neonatal cranial ultrasound.
- The incidence, natural history, and neurodevelopmental impact of FHC require further elucidation.
Purpose of the Study:
- To document the incidence and natural history of FHC in newborns.
- To compare the neurodevelopmental outcomes of infants with and without FHC.
Main Methods:
- A case-control study design was employed.
- Newborns with and without FHC were matched for demographics and cranial ultrasound (CUS) findings.
- Neurodevelopmental outcome was assessed at 18 to 24 months of age.
Main Results:
- Thirty cases of FHC were identified, with 25 occurring in preterm infants (<32 weeks gestation), yielding an incidence of 1%.
- FHC were diagnosed on initial CUS in most cases, with stable size and number on repeat scans.
- No statistically significant differences in neurodevelopmental outcomes were observed between the FHC and control groups.
Conclusions:
- Frontal horn cysts are not uncommon in the newborn period.
- FHC appear to be benign lesions with no discernible impact on neurodevelopmental outcomes.
- This finding is crucial for parental counseling regarding FHC.
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