Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Some epidemiological models with nonlinear incidence.

H W Hethcote1, P van den Driessche

  • 1Department of Mathematics, University of Iowa, Iowa City 52242.

Journal of Mathematical Biology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrospective analysis of age-specific non-pharmaceutical interventions on wild-type SARS-CoV-2 in Canada.

BMC public health·2026
Same author

Estimation of the exponential growth rate of an epidemic.

Infectious Disease Modelling·2026
Same author

Distributions of prevalence and daily new cases in a stochastic linear SEIR model.

Mathematical biosciences·2025
Same author

Estimating the effect of contact tracing during the early stage of an epidemic.

Infectious Disease Modelling·2025
Same author

A selfish supergene causes meiotic drive through both sexes in <i>Drosophila</i>.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

A mathematical model to assess the impact of testing and isolation compliance on the transmission of COVID-19.

Infectious Disease Modelling·2023
Same journal

Phenotypic plasticity trade-offs in an age-structured model of bacterial growth under stress.

Journal of mathematical biology·2026
Same journal

Intraspecific interactions facilitate mutualism across multilayer networks under weak selection.

Journal of mathematical biology·2026
Same journal

A two-species competition model on a compact metric graph for the invasion and competition of Aedes Aegypti and Aedes Albopictus mosquitoes in Florida.

Journal of mathematical biology·2026
Same journal

Superinfection and the hypnozoite reservoir for Plasmodium vivax: a multitype branching process approximation.

Journal of mathematical biology·2026
Same journal

Correction to: Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework.

Journal of mathematical biology·2026
Same journal

Stoichiometric balance and sustained rhythms.

Journal of mathematical biology·2026
See all related articles

Nonlinear epidemiological models exhibit complex dynamics, including multiple equilibria and periodic solutions, differing significantly from standard bilinear models. These findings are crucial for understanding disease spread with temporary immunity and delayed removal.

Area of Science:

  • Mathematical Epidemiology
  • Dynamical Systems Theory
  • Disease Modeling

Background:

  • Traditional epidemiological models often use bilinear incidence rates, which may oversimplify complex disease dynamics.
  • Nonlinear incidence rates can lead to richer and more varied mathematical behaviors in disease transmission models.
  • Understanding disease dynamics is critical for public health interventions and policy-making.

Purpose of the Study:

  • To investigate the dynamic behaviors of epidemiological models incorporating nonlinear incidence rates.
  • To analyze models with vital dynamics, temporary immunity, and delayed removal.
  • To identify conditions leading to multiple equilibria and periodic solutions (Hopf bifurcation).

Main Methods:

  • Analysis of epidemiological models with nonlinear incidence.

Related Experiment Videos

  • Investigation of equilibria and their stability.
  • Application of Hopf bifurcation theory to identify periodic solutions.
  • Main Results:

    • Nonlinear incidence rates lead to significantly different dynamics compared to bilinear rates.
    • Models with temporary immunity and vital dynamics can exhibit multiple equilibria.
    • Hopf bifurcation can generate periodic solutions from endemic equilibria in these nonlinear models.
    • Analogous results were found for a second model featuring a delay in the removed class.

    Conclusions:

    • Nonlinear incidence rates are essential for capturing complex behaviors in epidemiological models.
    • The presence of multiple equilibria and periodic solutions highlights the potential for intricate disease dynamics.
    • These findings provide a more nuanced understanding of disease transmission patterns under specific epidemiological conditions.