Related Experiment Video
Updated: Jun 11, 2026

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
Published on: February 18, 2022
The heart failure epidemic
1Division of Cardiovascular Diseases, Department of Internal Medicine and the Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. roger.veronique@mayo.edu
Insights
The heart failure epidemic is driven by increased survival, not incidence. This means more people are hospitalized for heart failure, highlighting the need for better hospitalization management strategies.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Heart failure (HF) is recognized as an emerging epidemic.
- Understanding factors contributing to HF prevalence is vital for effective prevention strategies.
Purpose of the Study:
- To analyze temporal trends in heart failure incidence and prevalence.
- To investigate changes in heart failure based on ejection fraction over time.
- To identify the primary drivers of the heart failure epidemic.
Main Methods:
- Review of population-based studies examining heart failure trends.
- Analysis of incidence, prevalence, and survival data over time.
- Assessment of heart failure epidemic's components: incidence versus survival.
Main Results:
- Heart failure incidence has remained relatively stable over time.
- Survival rates for heart failure patients have significantly improved.
- The increasing prevalence of heart failure is primarily due to improved survival, leading to more hospitalizations.
Conclusions:
- The heart failure epidemic is largely characterized by an increase in hospitalizations.
- Further research on temporal trends by ejection fraction is necessary.
- Interventions should prioritize reducing the hospitalization burden in heart failure management.
Abstract:
Heart failure has been singled out as an emerging epidemic, which could be the result of increased incidence and/or increased survival leading to increased prevalence. Knowledge of the responsibility of each factor in the genesis of the epidemic is crucial for prevention. Population-based studies have shown that, over time, the incidence of heart failure remained overall stable, while survival improved. Therefore, the heart failure epidemic is chiefly one of hospitalizations. Data on temporal trends in the incidence and prevalence of heart failure according to ejection fraction and how it may have changed over time are needed while interventions should focus on reducing the burden of hospitalizations in hear failure.
Related Concept Videos
Heart Failure I: Introduction
Pathophysiology of Heart Failure
Heart Failure III: Clinical Manifestations
Heart Failure II: Pathophysiology
Heart Failure V: Medical Management
Heart Failure IV: Classification and Diagnostic Evaluation
