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Related Experiment Video

Updated: Jun 11, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Endodontic emergencies: Your medication may be the cause.

Promila Verma¹, Anil Chandra, Rakesh Yadav

¹Department of Operative Dentistry, Faculty of Dental Sciences, Chatrapati Sahuji Maharaj Medical University, Lucknow, India.

Journal of Conservative Dentistry : JCD

|July 10, 2010

Summary

Formocresol, a dental pulp medicament, can cause severe oral soft tissue and gingival necrosis. This case highlights the risks associated with formocresol use during endodontic therapy.

Keywords:

Formocresol necrosis paraformaldehyde containing paste

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Area of Science:

Dentistry
Endodontics
Oral Pathology

Background:

Root canal treatment aims to preserve tooth function and prevent infection.
Formocresol is a medicament historically used in endodontics for pulp devitalization and disinfection.
Unwanted complications can arise during endodontic procedures, necessitating careful material selection and application.

Observation:

A case of severe soft tissue and gingival necrosis in the oral cavity is reported.
The necrosis occurred following the application of formocresol during endodontic treatment.
The clinical presentation indicated an unusual and severe adverse reaction to the medicament.

Findings:

Formocresol, when used in endodontic treatment, can lead to significant iatrogenic damage.
The necrosis observed involved both the gingival tissues and adjacent oral soft tissues.
This case underscores the potential for severe local tissue destruction from formocresol exposure.

Implications:

Clinicians should exercise extreme caution when considering formocresol for endodontic procedures.
Alternative medicaments with a better safety profile should be prioritized to avoid such adverse events.
This case emphasizes the importance of understanding the risks and benefits of all materials used in endodontic therapy.