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Quantifying the duration of pre-diabetes.
1Centre for Burden of Disease and Cost-Effectiveness, School of Population Health, Edith Cavell Building, Herston Rd, Herston QLD 4006. m.bertram@sph.uq.edu.au
Australian and New Zealand Journal of Public Health
|July 13, 2010
Summary
Pre-diabetes in Australia lasts over 8 years, indicating a need for screening. This duration supports implementing early detection programs to manage pre-diabetes effectively.
Area of Science:
- Public Health
- Epidemiology
- Metabolic Health
Background:
- Pre-diabetes interventions are effective, but Australia lacks a systematic identification process.
- Early detection of pre-diabetes is crucial for timely intervention and disease prevention.
Purpose of the Study:
- To calculate the duration of pre-diabetes in Australia.
- To provide evidence supporting the implementation of a pre-diabetes screening program.
Main Methods:
- A systematic review and random-effects meta-analysis were conducted to assess mortality risk in pre-diabetes.
- Data on prevalence, remission, and transition to diabetes from an Australian cohort study were utilized.
- The DisMod software program was employed to estimate the duration of pre-diabetes.
Main Results:
- The meta-analysis of 11 studies found a pooled relative risk of all-cause mortality of 1.26 (1.17-1.34) in individuals with pre-diabetes.
- The average duration of pre-diabetes was estimated to be 8.5 years for males aged 30+ and 10.3 years for females aged 30+.
Conclusions:
- The calculated duration of pre-diabetes in Australia is substantial, justifying the development of a screening program.
- The findings remain robust even with significant variations in epidemiological parameters.
- A screening program for pre-diabetes is strongly recommended if subsequent interventions prove cost-effective.
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