Related Experiment Video
Updated: Jun 11, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Anticipating maximal or submaximal exercise: no differences in cardiopulmonary responses
Ida Kjelkenes1, Einar Thorsen1,2
1Institute of Medicine, University of Bergen, Bergen.
Background:
Anticipation before the start of exercise may influence the cardiopulmonary responses during exercise. If anticipation influences the responses differently with maximal and submaximal exercises, normative values for submaximal responses will not be comparable unless exercise has been continued to the same end point.
Methods:
Twelve healthy subjects (five men) aged 18-27 years had a maximal exercise test and a submaximal exercise test on a cycle ergometer on different days and in random order. They were not aware of the specific purpose of the study and were informed 15 min before the tests whether it should be maximal or submaximal. Workload increased with 15 W min(-1) until exhaustion or to 80% of predicted maximal heart rate (HR). HR, oxygen uptake (VO(2)), carbon dioxide production (VCO(2)), minute ventilation (V(E)) and tidal volume (V(T)) were averaged over 20 s intervals. Linear regression of the HR-VO(2) relationship and quadratic regression of the V(T)-V(E) relationship were performed for each individual, and the regression coefficients for maximal and submaximal tests were compared.
Results:
The regression models described the V(T)-V(E) responses with a R(2) > 0.85 in 23 of 24 tests, and the HR-VO(2) responses with a R(2) > 0.90 in all tests. The regression coefficients of the relationships were not significantly different with maximal and submaximal exercises.
Conclusion:
Anticipation appears not to influence the responses to progressive maximal and submaximal exercise tests with the same rate of increase in load. Normative values at submaximal exercise levels are not influenced by the targeted end point of exercise.
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...

