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Updated: Jun 11, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

Tuberous sclerosis: a case report.

Nicola Jayne Cross¹, Diane E Fung

¹Glasgow Dental Hospital and School, Glasgow, Scotland. nicolacross20@hotmail.com

Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

|July 13, 2010

Summary

Tuberous sclerosis, a rare genetic disorder, can cause fibrous oral lesions on the gums. Dental care for patients with tuberous sclerosis requires special consideration due to potential complications like epilepsy.

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Last Updated: Jun 11, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

Area of Science:

Genetics
Neurology
Dermatology

Background:

Tuberous sclerosis is an inherited neurocutaneous disorder affecting approximately 1 in 7,500 live births.
It is characterized by benign neoplasms in multiple organs, including the skin, heart, kidneys, lungs, and central nervous system.
Oral manifestations, typically fibrous growths on the anterior gingivae, can occur.

Observation:

A 10-year-old girl with a history of tuberous sclerosis presented with a leafy gingival growth during a routine dental check-up.
An excisional biopsy was performed to investigate the lesion.
Histological examination revealed nonspecific findings consistent with tuberous sclerosis.

Findings:

Tuberous sclerosis can present with distinct oral manifestations, such as gingival growths.
Patients with tuberous sclerosis may experience associated conditions like epilepsy and learning difficulties.
The histological appearance, though nonspecific, supported the diagnosis in this case.

Implications:

Early detection and recognition of oral lesions in tuberous sclerosis patients are crucial.
Dental management requires careful planning due to potential complications like epilepsy and learning difficulties.
This case highlights the importance of a multidisciplinary approach to managing patients with tuberous sclerosis and its oral manifestations.