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Updated: Jun 11, 2026

Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
Published on: July 28, 2023
[Three years of Q fever in the Netherlands: faster diagnosis]
Wim van der Hoek1, Frederika Dijkstra, Nancy Wijers
1Rijksinstituut voor Volksgezondheid en Milieu, Bilthoven, Centrum Infectieziektebestrijding, the Netherlands. wim.van.der.hoek@rivm.nl
Objective:
To assess if more rapid diagnosis and treatment is possible and to assess if this could be improved, since the first outbreak of Q fever in 2007.
Design:
Retrospective study of secondary data.
Methods:
Analysis of surveillance data regarding Q fever over the period 2007 to 2009 and additional information on some patients from 2007 and 2008 obtained from general practitioners.
Results:
Diagnostic delay fell sharply between 2007 and 2009 and to a lesser extent, so did therapeutic delay from 2007 to 2008. In high incidence areas, diagnosis and treatment was faster with a lower proportion of patients admitted to hospital than in low incidence areas.
Conclusion:
It appears that familiarity with the condition leads to faster diagnosis coupled with a lower percentage of hospital admissions. In order to react quickly it is necessary that doctor and patient should be aware of Q fever, especially in areas of low incidence. Polymerase chain reaction diagnostic techniques should also be available.
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