Related Experiment Video
Updated: Jun 11, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Portomesenteric venous thrombosis associated with rectal venous malformations
Ann M Kulungowski1, Victor L Fox, Patricia E Burrows
1Department of Surgery, Children's Hospital Boston, Boston, MA 02115, USA.
Rectal venous malformations (VMs) with ectatic mesenteric veins increase the risk of portomesenteric venous thrombosis (PVT). Early evaluation and management are crucial for patients with this pattern to prevent serious complications.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Radiology
Background:
- Rectal venous malformations (VMs) are uncommon vascular anomalies.
- Portomesenteric venous thrombosis (PVT) is a serious condition with significant morbidity and mortality.
Purpose of the Study:
- To investigate the association between rectal VMs and ectatic mesenteric veins.
- To determine the risk of PVT in patients with this specific vascular pattern.
Main Methods:
- Retrospective review of eight patients with rectal VMs and associated ectatic mesenteric veins or PVT.
- Evaluation of clinical data, imaging, and outcomes from 1995-2009.
Main Results:
- Five patients presented with PVT.
- Six patients developed portal hypertension.
- One patient underwent preemptive inferior mesenteric vein ligation.
Conclusions:
- Rectal VMs associated with ectatic mesenteric veins represent a risk factor for PVT.
- Ectatic veins can cause blood flow stagnation, leading to thrombosis.
- Prompt recognition and management are essential for preventing PVT progression.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
Esophageal Varices-I: Introduction
Varicose Veins I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
