Hemostasis in thyroid surgery: harmonic scalpel versus other techniques--a meta-analysis
Thomas Ecker1, Andre Lopes Carvalho, Jun-Ho Choe
1EPC HealthCare GmbH, Hamburg, Germany. t.ecker@epc-healthcare.de
Summary
The harmonic scalpel significantly reduces operating time and blood loss during thyroid surgery compared to other methods. This advanced surgical tool also lowers postoperative pain without increasing complications or hospital stay.
Area of Science:
- Surgical Technology
- Minimally Invasive Surgery
- Endocrine Surgery
Background:
- Thyroidectomy is a common procedure with ongoing debate on optimal hemostasis techniques.
- Achieving safe, efficient, and cost-effective hemostasis is crucial in thyroid surgery.
Purpose of the Study:
- To systematically review and analyze literature comparing the harmonic scalpel with other hemostatic methods in thyroid surgery.
- To evaluate the efficacy and safety of the harmonic scalpel for hemostasis in thyroidectomy patients.
Main Methods:
- A systematic literature search was conducted using Medline and the Cochrane Library.
- Twelve prospective randomized controlled studies involving 1153 patients were included in this meta-analysis.
- Data were independently assessed by two reviewers.
Main Results:
- The harmonic scalpel significantly reduced operating time by approximately 25% (22.67 minutes) and blood loss by 20.03 mL.
- A statistically significant reduction in postoperative pain (0.86 points) and a trend towards shorter hospital stays (0.12 days) were observed.
- No significant differences were found in drainage fluid volume or complication rates compared to traditional methods.
Conclusions:
- The harmonic scalpel is a highly effective tool for achieving hemostasis in thyroid surgery.
- Its use leads to significant reductions in operative time and blood loss.
- The harmonic scalpel does not increase complication rates or drainage fluid volume, supporting its adoption in thyroidectomy.

