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Related Experiment Video

Updated: Jun 11, 2026

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

Nutrition and nail disease.

Michael W Cashman¹, Steven Brett Sloan

¹George Washington University School of Medicine, 2300 Eye Street NW, Washington, DC 20037, USA.

Clinics in Dermatology

|July 13, 2010

Summary

Nail disorders are common dermatologic conditions. Nutritional deficiencies can significantly impact nail growth and health, with supplements like biotin showing promise for treatment.

Area of Science:

Dermatology
Nail Biology
Nutritional Science

Background:

Nail disorders represent about 10% of dermatologic conditions.
The nail unit comprises the hyponychium, nail bed, proximal nail fold, and matrix.
Understanding nail anatomy and chemical composition is crucial for diagnosing disorders.

Purpose of the Study:

To provide an overview of nail anatomy and function.
To review the chemical profile of the normal nail plate.
To discuss nail manifestations of malnutrition and potential treatments.

Main Methods:

Literature review of nail anatomy, physiology, and biochemistry.
Analysis of nutritional deficiencies affecting nail health.
Review of current literature on supplements for nail disorders.

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Main Results:

Nail growth is approximately 2-3 mm/month, with full replacement in 6-9 months.
The nail plate is rich in keratin, sulfur, and various minerals.
Nutritional deficiencies manifest in various nail abnormalities.

Conclusions:

Nail disorders are prevalent and linked to nutritional status.
Dietary interventions and supplements may improve nail health.
Biotin shows potential for treating specific nail conditions like brittle nail syndrome.