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Updated: Aug 23, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
Published on: June 15, 2016
On the prevalence of transcriptional regions in human genomic DNA
1Department of Molecular and Experimental Medicine, Research Institute of Scripps Clinic, La Jolla, California 92037.
Abstract:
The dinucleotide sequences TpA and CpG are differentially expressed in transcribed vs. non-transcribed portions of the human genome (Beutler et al., 1989, Proc. natn. Acad. Sci. U.S.A. 86, 192-196). This fact is exploited here to estimate the total number of transcriptional regions in human genomic DNA.
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