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Amyloid formation in insulinoma.

T An, G I Kaye

    Archives of Pathology & Laboratory Medicine
    |May 1, 1978
    PubMed
    Summary

    Neoplastic beta cells in pancreatic adenomas actively form amyloid deposits. Electron microscopy revealed cellular invaginations and processes contributing to amyloid structure in insulinomas.

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    Area of Science:

    • Endocrinology
    • Cell Biology
    • Pathology

    Background:

    • Amyloidosis is characterized by extracellular protein deposits.
    • Beta cell adenomas (insulinomas) are pancreatic tumors.
    • The specific mechanisms of amyloid formation in insulinomas are not fully understood.