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Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
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Drug resistance in mutant FLT3-positive AML.

E Weisberg1, M Sattler, A Ray

  • 1Department of Medical Oncology/Hematologic Neoplasia, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Ellen_Weisberg@dfci.harvard.edu

Oncogene
|July 13, 2010
PubMed
Summary

Mutant Fms-Like Tyrosine kinase-3 (FLT3) inhibitors show promise for acute myeloid leukemia (AML) therapy, but resistance is a growing concern. This study explores FLT3

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