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Updated: Jun 11, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
A rare association: basal cell carcinoma in a vitiliginous macula
Jan Rustemeyer1, Lutz Günther, Linda Deichert
1Department of Oral and Maxillofacial Surgery, Klinikum Bremen-Mitte, School of Medicine of the University of Göttingen, Bremen, Germany. janrustem@gmx.de
Background:
Today, no proven significant association was detected between sun-exposed vitiliginous patches and non-melanotic skin cancers. In fact, the occurrence of a basal cell carcinoma (BCC) in vitiliginous patches seems to be extremely rare.
Case Report:
We present a case of a 33-year-old female patient suffering from BCC in a vitiliginous patch on the cheek. This is the first report of the occurrence of a sclerodermiform type of BCC in a vitiliginous macula.
Conclusion:
Our case report challenges the long-standing belief that the occurrence of BCC in vitiligo is nearly impossible. However, even if this association is apparently fortuitous, our report contributes to the awareness of the risk of BCC in young patients with vitiligo.
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