Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...

Group Design

Group Design

The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between the two are due to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Human-centered evaluation of statistical parametric mapping and explainable machine learning for outlier detection in plantar pressure data.

Scientific reports·2026

Same author

Effects of sensorimotor foot orthoses on static balance in healthy adults: a crossover randomized controlled trial.

Frontiers in sports and active living·2025

Same author

Exploratory analysis of critical event phases and the impact of team size and performance levels in 24 hour ultra cycling.

PloS one·2025

Same author

A potential relationship between soccer shoes and pes cavus: a pilot study.

BMC sports science, medicine & rehabilitation·2025

Same author

Ergogenic effects of supplement combinations on endurance performance: a systematic review and meta-analysis of randomized controlled trials.

Journal of the International Society of Sports Nutrition·2025

Same author

Toward automated plantar pressure analysis: machine learning-based segmentation and key point detection across multicenter data.

Frontiers in bioengineering and biotechnology·2025

Search research articles

Related Experiment Video

Updated: Jun 11, 2026

Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

Published on: May 9, 2019

Outcome effects of single-set versus multiple-set training--an advanced replication study.

Michael Fröhlich¹, Eike Emrich, Dietmar Schmidtbleicher

¹Institute of Sports Sciences, University of Saarland, Institute of Sports Sciences, 66123 Saarbrücken, Germany. m.froehlich@mx.uni-saarland.de

Research in Sports Medicine (Print)

|July 13, 2010

Summary

Multiple-set strength training (MST) offers advantages over single-set training (SST) for long-term strength gains, especially for advanced individuals. Short-term interventions show similar outcomes for both methods.

More Related Videos

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Related Experiment Videos

Last Updated: Jun 11, 2026

Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

Published on: May 9, 2019

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Area of Science:

Exercise Physiology
Sports Science
Strength and Conditioning

Background:

The efficacy of single-set training (SST) versus multiple-set training (MST) in strength development is a key consideration in exercise programming.
This review critically examines the existing literature to compare these two fundamental training approaches.

Purpose of the Study:

To conduct a meta-analysis comparing the effectiveness of single-set training (SST) versus multiple-set training (MST).
To identify factors influencing the comparative effectiveness of SST and MST across various training interventions and populations.

Main Methods:

A meta-analysis of 72 primary studies was performed to evaluate the effectiveness of SST versus MST.
Effect sizes were calculated and analyzed in relation to variables such as age, training experience, and intervention duration.

Main Results:

Multiple-set training (MST) demonstrates advantages over single-set training (SST), particularly when integrated with periodization strategies for long-term maximal strength enhancement.
For short-term interventions, both SST and MST yield comparable outcomes.
MST is statistically superior for advanced trainees aiming to optimize strength gains over longer intervention periods.

Conclusions:

Multiple-set training (MST) is generally more effective than single-set training (SST) for maximizing strength gains, especially in the long term and for experienced individuals.
The choice between SST and MST should consider intervention duration and the training status of the individual.
Periodization strategies enhance the effectiveness of MST for long-term strength development.