Related Experiment Video
Updated: Jun 11, 2026

Effects of Desmodium caudatum on Gastrointestinal Hormones and Intestinal Flora in Rats with Gastritis
Published on: March 1, 2024
Anti-heartburn effects of a fenugreek fiber product
Robert A DiSilvestro1, Marian A Verbruggen, E Jann Offutt
1Columbus Nutraceuticals Consulting Inc., Dublin, OH 43016-9062, USA. studies@columbus.rr.com
Abstract:
Frequent heartburn occurs in many people, some of whom prefer alternative treatments over conventional drugs. In a pilot study of subjects with frequent heartburn, 2 week intake of a fenugreek fiber product, taken 30 min before two meals/day, diminished heartburn severity. This conclusion was based on symptom diary results and reduced the use of a mild antacid as a rescue medicine. Improvement for each of the 2 weeks was judged by comparison with results from a baseline week. Placebo also produced some statistically significant effects, but the fiber product's effects differed significantly from the placebo. Moreover, the fenugreek fiber effects were generally similar to the results produced by an OTC antacid medication (ranitidine at 75 mg, twice a day). This study suggests that people with certain degrees of heartburn can benefit from a fenugreek fiber product.
Related Concept Videos
Acid Suppressive Drugs for Peptic Ulcer Disease: Histamine H2-Receptor Antagonists
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antianginal Drugs: Nitrates and β-Blockers
Organic nitrates, such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow. Administered...
Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids
However, this neutralization reaction between...
Drug toxicity: Drug–Drug Interaction