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Related Concept Videos

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Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
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Transient Transduction of the Strobilated Forms of Echinococcus granulosus
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Published on: September 16, 2022

Echinococcosis with particular reference to Southeast Asia.

Donald P McManus1

  • 1Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia.

Advances in Parasitology
|July 14, 2010
PubMed
Summary
This summary is machine-generated.

Echinococcosis, caused by Echinococcus parasites, presents significant public health challenges globally. New strategies are crucial for preventing and controlling cystic echinococcosis (CE) and alveolar echinococcosis (AE).

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Area of Science:

  • Zoonotic diseases
  • Parasitology
  • Public health

Background:

  • Echinococcosis is a zoonotic disease caused by Echinococcus cestodes, primarily E. granulosus (cystic echinococcosis, CE) and E. multilocularis (alveolar echinococcosis, AE).
  • Both CE and AE are severe diseases with high fatality rates, increasingly recognized as emerging or re-emerging public health concerns.
  • Echinococcosis affects global health, with particular attention to distribution and transmission in Southeast Asia.

Purpose of the Study:

  • To review the biology, life cycle, distribution, and transmission of Echinococcus species.
  • To cover the epidemiology, clinical features, diagnosis, and treatment of CE and AE.
  • To assess current control and prevention strategies, including animal vaccines, and identify needs for new advances.

Main Methods:

  • Literature review of Echinococcus biology, epidemiology, and disease characteristics.
  • Analysis of global and regional distribution and transmission patterns.
  • Evaluation of existing and potential control and prevention measures for CE and AE.

Main Results:

  • E. granulosus causing CE has a wide distribution, with some regions achieving effective control.
  • E. multilocularis causing AE is more challenging to control due to its sylvatic transmission cycle.
  • Chemotherapy aids in less invasive management of both CE and AE.

Conclusions:

  • There is a significant need for novel approaches to prevent and control echinococcosis, particularly AE.
  • Integrated strategies are required to address the global burden of these neglected zoonotic diseases.
  • Further research and development are essential for effective echinococcosis management.