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Published on: January 29, 2011
Duration of illness in infants with bronchiolitis evaluated in the emergency department
Frank D Petruzella1, Marc H Gorelick
1Division of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. fpetruze@mcw.edu
Insights
Infants with first-time bronchiolitis experience prolonged illness, often lasting over three weeks. This condition significantly impacts families, with caregivers missing work and children requiring additional medical visits.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Bronchiolitis is a common viral respiratory infection in infants.
- First-time episodes in the emergency department (ED) setting warrant further investigation into disease duration and family impact.
Purpose of the Study:
- To determine the duration of illness in infants experiencing their first episode of bronchiolitis presenting to an ED.
- To evaluate the associated burden on caregivers and families.
Main Methods:
- Prospective cohort study of infants under 12 months with first-time bronchiolitis.
- Exclusion criteria included prior bronchodilator use or immunocompromise.
- Data collected via ED assessment and weekly telephone interviews for up to 4 weeks.
Main Results:
- Median symptom duration was 15 days, with 25% symptomatic beyond 21 days.
- A history of eczema showed a trend towards longer symptom duration (18 days vs. 15 days).
- Daycare and work absences were significant, with 37.1% of infants having subsequent unscheduled medical visits.
Conclusions:
- Infants with bronchiolitis presenting to the ED often have a prolonged illness course.
- Family burden is substantial, including missed work and subsequent medical care needs.
- Potential influence of atopy on symptom duration suggests a need for informed family counseling.
Objectives:
To describe the duration of illness in infants with first-time bronchiolitis who present to an emergency department (ED) and assess the burden of the illness on caregivers and families.
Methods:
This was a prospective cohort study of infants younger than 12 months who presented to a tertiary care children's hospital ED with a first episode of bronchiolitis. Subjects were excluded if they had a history of bronchodilator use or immunocompromise. Demographic and clinical data were collected in the ED. Outcomes data were collected by weekly telephone interviews for 4 weeks or until the subject was free of cough for 24 hours.
Results:
Ninety-five infants were enrolled from November 2007 to March 2008. Median duration of symptoms was 15 days; 25% of the infants remained symptomatic after 21 days. Subjects with a history of eczema trended toward a longer median duration of symptoms when compared with those who did not (18 days [interquartile range (IQR): 15.5-24] and 15 days [IQR: 11-19], respectively; P = .055). Duration of symptoms did not significantly vary with regards to respiratory syncytial virus status or secondhand smoke exposure. Subjects missed a median of 2.5 days (IQR: 0.5-5.5) of day care, and caregivers missed a median of 2 days (IQR: 1-4) of work. Of these infants, 37.1% (95% confidence interval: 24.3-44.1) had a subsequent unscheduled medical visit.
Conclusions:
Infants seen in the ED for bronchiolitis have a prolonged disease course, with substantial burden to the family. Symptom duration may be influenced by a propensity toward atopy. Clinicians may use this information for counseling families.
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