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Updated: Jun 11, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)
Published on: March 7, 2017
Pediatric gliomatosis cerebri mimicking acute disseminated encephalomyelitis
Hope T Richard1, Jason F Harrison, Ty W Abel
1College of Medicine, University of South Alabama, Mobile, AL 366, USA. jsosnowski@usouthal.edu
Abstract:
Gliomatosis cerebri (GC) is a diffuse infiltrating glial neoplasm of astrocytic origin. GC in children is rare and difficult to diagnose, often presenting with a variety of signs and symptoms that may mimic encephalitis. We discuss here the presentation and diagnosis of GC in 2 children who were initially suspected to have acute disseminating encephalomyelitis. In this report we underscore the limitations of relying on clinical presentation and neuroimaging as well as the essential role of pathologic evaluation for the diagnosis of GC in children.
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