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Updated: Jun 11, 2026

Osteoclast Derivation from Mouse Bone Marrow
Published on: November 6, 2014
Sex hormones and bone health in males
Vincenzo Carnevale1, Elisabetta Romagnoli, Cristiana Cipriani
1Casa Sollievo della Sofferenza Hospital, IRCCS, Viale dei Cappuccini, 71013 San Giovanni Rotondo, Italy. venz.carnevale@libero.it
Abstract:
Sex steroids play a key role in maintaining skeletal integrity lifelong, through a complex variety of endocrine, but also paracrine and possibly autocrine actions. The current knowledge that androgens may act as pro-hormones for estrogens has seriously challenged many traditional views, so that, at least for their skeletal actions, these can no longer be considered exclusively "male" or "female" hormones.
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