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Updated: Jun 11, 2026

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
Published on: March 26, 2019
The enigma of vasculitis
Daniela Ghetie1, Alla Rudinskaya, Raymond Raut
1Department of Medicine (Rheumatology and Nephrology & Hypertension), Danbury Hospital, Danbury, CT 06810, Valhalla, NY 10595, USA.
Abstract:
We describe the case of an 86-year-old man presenting with clinical symptoms suggestive of Temporal Arteritis. The evolution of the case prompted extensive work-up, including temporal artery and kidney biopsy. Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made. The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab. The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.
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