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Published on: February 27, 2026
Successfully resected intrathoracic low-grade fibromyxoid sarcoma
Mitsunori Higuchi1, Hiroyuki Suzuki, Yutaka Shio
1Division of Thoracic Surgery, Department of Surgery 1, Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima 960-1295, Japan. higuchi@fmu.ac.jp
General Thoracic and Cardiovascular Surgery
|July 15, 2010
Summary
A rare low-grade fibromyxoid sarcoma (LGFMS) was found in a young woman's chest. Surgical removal was successful, with no recurrence after 18 months, highlighting effective treatment for this unusual thoracic neoplasm.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor.
- Primary LGFMS in the thoracic cavity is exceptionally uncommon.
- This case presents a unique instance of LGFMS within the chest.
Observation:
- A 20-year-old female presented with a right intrathoracic tumor.
- Diagnostic workup included histological examination and immunohistochemical staining.
- Fluorescence in situ hybridization confirmed FUS translocation, characteristic of LGFMS.
Findings:
- The resected tumor was definitively diagnosed as LGFMS.
- Surgical resection achieved clear margins.
- The chest wall defect was successfully reconstructed with prosthetic mesh.
Implications:
- This case expands the understanding of LGFMS presentation.
- It demonstrates the feasibility of complete surgical resection for thoracic LGFMS.
- Successful management offers a positive prognosis for similar rare thoracic neoplasms.
