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Ratiometric fluorescent detection of an anthrax biomarker at molecular printboards

M Deniz Yilmaz1, Shu-Han Hsu, David N Reinhoudt

  • 1Molecular Nanofabrication Group, MESA+Institute for Nanotechnology, University of Twente, 7500 AE, Enschede, The Netherlands.

Angewandte Chemie (International Ed. in English)
|July 15, 2010
PubMed
Abstract

No abstract available in PubMed .

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...