Related Experiment Video

Updated: Jun 11, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Perimetric severity in hospital-based and population-based glaucoma patients

S Ve Ramesh1, Ronnie George, Prema Raju

  • 1Glaucoma Project, Vision Research Foundation, Sankara Nethralaya, Chennai, India.

Clinical & Experimental Optometry
|July 16, 2010
PubMed

Insights

Newly diagnosed glaucoma patients at a hospital had higher intraocular pressure (IOP) and more severe visual field defects compared to those in a population study. Hospital-based study results on glaucoma severity require careful interpretation.

Area of Science:

  • Ophthalmology
  • Public Health
  • Glaucoma Research

Background:

  • Glaucoma severity assessment often relies on hospital-based data.
  • Population-based studies offer a different perspective on disease prevalence and severity.

Purpose of the Study:

  • To compare the severity of primary glaucoma in newly diagnosed patients at a hospital-based glaucoma care center (HBGS) with age-matched individuals from a population-based study (CGFS).

Main Methods:

  • Included newly diagnosed primary glaucoma patients from HBGS and age/gender-matched controls from CGFS.
  • Comprehensive ocular examinations, including Humphrey visual field (HVF) testing (24-2 SITA Standard).
  • Glaucoma defined by intraocular pressure (IOP), vertical cup-to-disc ratio (VCDR), and visual field parameters; analysis at the third follow-up visit.

Main Results:

  • Forty-seven age-matched subjects were analyzed.
  • HBGS patients exhibited significantly higher IOP (mean difference: 2.80 mmHg, p=0.04).
  • HBGS patients showed more severe visual field defects, with statistically significant differences in mean deviation (p=0.036) and pattern standard deviation (p=0.0001).

Conclusions:

  • Hospital-based glaucoma patients present with higher IOP and more advanced visual field loss than those in population-based studies.
  • Findings suggest caution when interpreting glaucoma severity and progression rates from hospital-based research alone.
Abstract

More Related Videos

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...