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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Methods for Studying Drug Absorption: In situ01:09

Methods for Studying Drug Absorption: In situ

In situ experiments, such as the Doluisio method and Single-Pass Perfusion technique, provide critical insights into drug uptake by simulating in vivo conditions for drug absorption.
The Doluisio method involves perfusing a prepared segment of a rat's small intestine with a solution of radiolabeled drug and a non-absorbable marker. This helps to differentiate between absorbed and non-absorbed drug concentrations. The intestinal segment is connected at both ends using tubing and syringes,...
Water and Mineral Acquisition02:34

Water and Mineral Acquisition

Specialized tissues in plant roots have evolved to capture water, minerals, and some ions from the soil. Roots exhibit a variety of branching patterns that facilitate this process. The outermost root cells have specialized structures called root hairs that increase the root surface, thus increasing soil contact. Water can passively cross into roots, as the concentration of water in the soil is higher than that of the root tissue. Minerals, in contrast, are actively transported into root cells.
Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the goblet,...
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

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Related Experiment Video

Updated: Jun 10, 2026

An Optimized Rhizobox Protocol to Visualize Root Growth and Responsiveness to Localized Nutrients
07:45

An Optimized Rhizobox Protocol to Visualize Root Growth and Responsiveness to Localized Nutrients

Published on: October 22, 2018

Internal root resorption: a review.

Shanon Patel1, Domenico Ricucci, Conor Durak

  • 1Endodontic Postgraduate Unit, King's College, London Dental Institute, London, United Kingdom.

Journal of Endodontics
|July 16, 2010
PubMed
Summary
This summary is machine-generated.

Internal root resorption involves dentin destruction and can manifest as inflammatory or replacement resorption. Cone beam computed tomography aids diagnosis, with root canal treatment remaining the primary therapy.

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Area of Science:

  • Endodontics
  • Dental Pathology

Background:

  • Internal root resorption is the progressive destruction of intraradicular dentin and dentinal tubules.
  • This process affects the middle and apical thirds of canal walls due to clastic activities.

Purpose of the Study:

  • To review the prevalence, etiology, pathogenesis, and histologic manifestations of internal root resorption.
  • To discuss differential diagnosis using cone beam computed tomography and current treatment perspectives.

Main Methods:

  • Literature review of existing case reports and studies.
  • Examination of histologic manifestations and biologic aspects.
  • Analysis of differential diagnosis with cone beam computed tomography.

Main Results:

  • Limited studies exist on histologic manifestations and biologic aspects due to rarity and lack of in vivo models.
  • Histologically, internal root resorption presents as destructive inflammatory resorption or repair-associated replacement resorption.
  • Replacement resorption involves deposition of metaplastic bone/cementum-like tissues.

Conclusions:

  • Cone beam computed tomography significantly improves the diagnosis of internal root resorption.
  • Root canal treatment is currently the established treatment of choice for this condition.