Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predictors of adequate correction following vision screening failure.

Optometry and vision science : official publication of the American Academy of Optometry·2012

Same author

Bevacizumab in conjunction with panretinal photocoagulation for neovascular glaucoma.

Optometry (St. Louis, Mo.)·2009

Same author

Descemet stripping and automated endothelial keratoplasty: an alternative to penetrating keratoplasty.

Optometry and vision science : official publication of the American Academy of Optometry·2008

Same author

Keep an eye out for glaucoma.

The Nurse practitioner·2007

Same author

Madarosis and facial alopecia presumed secondary to botulinum a toxin injections.

Optometry and vision science : official publication of the American Academy of Optometry·2005

Search research articles

Related Experiment Video

Updated: Jun 10, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Programs to optimize adherence in glaucoma.

Dianne Kowing¹, Dawn Messer, Scott Slagle

¹William Chappell Veterans Affairs Outpatient Clinic, Daytona Beach, FL, USA. Dianne.Kowing@va.gov

Optometry (St. Louis, Mo.)

|July 16, 2010

Summary

Improving glaucoma medication adherence is possible with various educational materials, digital tools, and innovative devices. These resources help patients manage their eye condition effectively.

Area of Science:

Ophthalmology
Pharmacology
Medical Technology

Background:

Glaucoma management requires consistent medication adherence for effective treatment.
Patient adherence to ocular hypotensive medications is a significant challenge in glaucoma care.

Purpose of the Study:

To raise awareness of available resources for improving glaucoma medication adherence.
To review emerging devices and technologies for enhanced glaucoma treatment.

Main Methods:

Comprehensive review of indexed literature.
Exploration of Internet-based resources and educational materials.

Main Results:

Numerous educational materials (brochures, fact sheets) are accessible online.

Related Experiment Videos

Last Updated: Jun 10, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Digital tools like videos, Web-based programs, and reminder systems (e-mail, PDA) support adherence.

Adherence-enhancing devices include dosing aids, timers, and electronic monitoring systems.

Novel drug delivery systems (nanoparticles, punctal plugs, drug-eluting contact lenses) are under development.

Conclusions:

A wide array of educational resources and technological devices exist to aid optometrists in promoting patient adherence.
These tools facilitate better glaucoma treatment and management outcomes.