Related Experiment Video
Updated: Jun 10, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
Published on: October 2, 2018
Caffeine as a photoprotective agent for diminishing phototoxicity
Yim Tong Szeto1, Henry H Y Tong
1Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology Foundation, Avenida Wai Long, Taipa, Macau SAR, PR China. savio.yim.tong.szeto@inet.polyu.edu.hk
Abstract:
Skin whitening with Chinese herbal medicine has been used in ancient Asia. However, phototoxicity of the active ingredient limits the application. The modified comet assay was used in the current study to detect DNA crosslinking induced by phototoxicity. Result showed that caffeine at 5 µmol/L was able to reduce 5-methoxypsoralen-induced phototoxicity with ultraviolet C (UVC) exposure.
Related Concept Videos
Photoreceptors and Plant Responses to Light
Photoreceptors and Visual Pathways
Drug Toxicity: Dose-Dependent Reactions
![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)
