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Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Loose Connective Tissue01:26

Loose Connective Tissue

Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...
Tissues01:25

Tissues

Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
Tissues01:18

Tissues

Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.

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Related Experiment Video

Updated: Jun 10, 2026

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
09:43

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Scar tissue.

Nick Jones

    Current Opinion in Otolaryngology & Head and Neck Surgery
    |July 16, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Effective scar treatment involves timing and scar type. Treatments like silicone sheets, pulsed dye laser (PDL), intralesional triamcinolone, and dermabrasion can reduce hypertrophic scars, but surgical revision should be delayed for at least 12 months.

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    A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
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    A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

    Published on: July 28, 2020

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    Last Updated: Jun 10, 2026

    Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
    09:43

    Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

    Published on: February 24, 2016

    A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
    07:15

    A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

    Published on: July 28, 2020

    Area of Science:

    • Dermatology
    • Plastic Surgery
    • Regenerative Medicine

    Background:

    • Scar tissue treatment is diverse, with many methods promoted online.
    • Understanding the efficacy and optimal application of various scar treatments is crucial.

    Purpose of the Study:

    • To evaluate the role of surgical scar revision versus other scar treatment modalities.
    • To provide evidence-based guidance on managing different types of scar tissue.

    Main Methods:

    • Review of current literature on scar treatment efficacy.
    • Analysis of evidence supporting interventions like silicone sheets, pulsed dye laser (PDL), intralesional triamcinolone, and dermabrasion.
    • Consideration of timing and scar type for treatment selection.

    Main Results:

    • Silicone sheets, PDL, intralesional triamcinolone, and dermabrasion show evidence in reducing hypertrophic scars.
    • Optimal timing and scar type are critical for the success of these interventions.
    • Surgical scar revision is generally recommended after 12 months of scar maturation, unless specific techniques like Z-plasty are needed earlier for contour irregularities.

    Conclusions:

    • Delayed surgical intervention (≥12 months) is advised for scar revision unless webbing necessitates early Z-plasty.
    • Triamcinolone injections and dermabrasion can address contour irregularities at specific post-operative intervals.
    • Silicone gel sheeting and PDL are effective for hypertrophic scarring, while time remains a key factor in scar maturation (18-24 months).
    • Further research into stem cell therapies for scar treatment is warranted.