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A case of Candida krusei peritonitis secondary to duodenal perforation due to Candida duodenitis
Antonio Cascio1, Marcello Bartolotta, Antonella Venneri
1Tropical and Parasitological Diseases Unit, Department of Human Pathology, University of Messina, Messina, Italy. acascio@unime.it
Abstract:
A case of a 62-year-old man with Candida krusei peritonitis secondary to duodenal perforation due to Candida duodenitis that was successfully treated with a 14-day course of caspofungin is reported. The potential role of Candida infection in the pathogenesis of peptic ulcers and duodenal perforation is considered. If this role is confirmed, antifungal treatment should be included in the therapeutic armamentarium of peptic disease.
Insights
A 62-year-old man recovered from Candida krusei peritonitis after duodenal perforation. Treatment involved a 14-day caspofungin course, suggesting a potential role for antifungals in peptic disease management.
Area of Science:
- Gastroenterology
- Mycology
- Infectious Diseases
Background:
- Duodenal perforation is a serious complication often associated with peptic ulcer disease.
- Candida infections, particularly Candida krusei, can lead to severe invasive conditions.
- The pathogenesis of peptic ulcers and duodenal perforations is multifactorial, but microbial roles are increasingly explored.
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